Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 8/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24829641 | 0.86 | CDK1 (0.53) | CDK1CDK2CCNB1CCNE1 | |
| SCHEMBL27385177 | 0.83 | CDK1 (0.40) | CDK1CDK2P2RY1ENPP1P2RY12 | |
| SCHEMBL21257337 | 0.81 | CDK1 (0.38) | CDK1CDK2P2RY1ENPP1P2RY12 | |
| SCHEMBL27426174 | 0.79 | CDK1 (0.37) | CDK1CDK2P2RY1ENPP1P2RY12 | |
| SCHEMBL21710849 | 0.78 | ADORA2A (0.49) | CDK1CDK2CCNB1CCNE1 | |
| SCHEMBL19049976 | 0.77 | HSP90AB1 (0.42) | CDK1CDK2CCNB1CCNE1 | |
| SCHEMBL19049964 | 0.76 | CDK1 (0.52) | CDK1CDK2CCNB1CCNE1 | |
| SCHEMBL23169714 | 0.76 | MEN1 (0.52) | BLMLMNAKMT2A | |
| SCHEMBL19464992 | 0.75 | CDK1 (0.41) | CDK1CDK2P2RY1ENPP1P2RY12 | |
| SCHEMBL27425667 | 0.73 | CDK1 (0.39) | CDK1CDK2P2RY1ENPP1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165887-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165887-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | TNNI3, CPT1B, TNNT2 | CDK1 2657/4885CDK2 3539/4885P2RY1 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.