Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560324 | 0.83 | PTGDR2 (0.57) | HSD17B10SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL6539788 | 0.79 | PARP1 (0.55) | HSD17B10SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL6538497 | 0.78 | ALDH1A1 (0.56) | HSD17B10SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL2559435 | 0.76 | MEN1 (0.49) | HSD17B10SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL11664167 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2LMNAALDH1A1HPGDPOLB | |
| SCHEMBL2562037 | 0.74 | ALDH1A1 (0.75) | SMN1; SMN2LMNAALDH1A1HPGDPOLB | |
| SCHEMBL2556136 | 0.74 | PTGDR2 (0.64) | HSD17B10SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL2554954 | 0.73 | SRC (0.50) | HSD17B10SMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL2558079 | 0.72 | HPGD (0.46) | SMN1; SMN2LMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL6538760 | 0.72 | HTT (0.52) | SMN1; SMN2LMNANPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |