Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560058 | 0.84 | SMN1; SMN2 (0.56) | HPGDNLRP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL2562136 | 0.76 | HPGD (0.51) | HPGDNLRP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL8258564 | 0.76 | CYP1A2 (0.61) | HPGDSMN1; SMN2KDM4ETDP1ALDH1A1 | |
| SCHEMBL15330229 | 0.74 | FDPS (0.63) | HPGDSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL7082489 | 0.73 | LMNA (0.54) | LMNAALDH1A1 | |
| SCHEMBL2559195 | 0.73 | NPC1 (0.49) | HPGDSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL2561469 | 0.72 | HSD17B10 (0.55) | HPGDSMN1; SMN2MAPK1LMNAKDM4E | |
| SCHEMBL2559643 | 0.72 | HPGD (0.65) | HPGDNLRP1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL2560871 | 0.71 | ALDH1A1 (0.51) | HPGDSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6369657 | 0.71 | SMN1; SMN2 (0.60) | HPGDSMN1; SMN2MAPK1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |