SCHEMBL25614897

SCHEMBL25614897

O=[N+]([O-])c1c(O)c(O)c(Cl)c(O)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
GPR35 Q9HC97 4/20 0.42
GRIN2D O15399 7/20 0.39
GRIN3B O60391 7/20 0.39
GRIN1 Q05586 7/20 0.39
GRIN2A Q12879 7/20 0.39
GRIN2B Q13224 7/20 0.39
GRIN2C Q14957 7/20 0.39
GRIN3A Q8TCU5 7/20 0.39
ALDH1A1 P00352 2/20 0.38
S100A4 P26447 1/20 0.38
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CDK2 P24941 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25615107 0.80 TSHR (0.39) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL25614863 0.80 TSHR (0.39) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL28688867 0.80 TSHR (0.46) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL9219776 0.80 TSHR (0.52) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL30589392 0.78 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL11819298 0.78 GPR35 (0.48) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL28685683 0.78 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL29105094 0.78 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
Ammonia Solution, Strong SCHEMBL30589376 0.78 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL30589375 0.78 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198020-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2023-06-21 EP disclosed