Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809855 | 0.71 | LRRK2 (0.39) | — | |
| SCHEMBL20778466 | 0.69 | PDE2A (0.34) | PDE2ADRD2KDM2B | |
| SCHEMBL20939178 | 0.67 | PRMT5 (0.40) | — | |
| SCHEMBL13684190 | 0.66 | — | — | |
| SCHEMBL23107185 | 0.65 | DRD4 (0.37) | DRD4DRD2DRD3 | |
| SCHEMBL20861490 | 0.65 | DRD4 (0.37) | DRD4DRD2DRD3 | |
| SCHEMBL23107178 | 0.65 | DRD4 (0.37) | DRD4DRD2DRD3 | |
| SCHEMBL24309011 | 0.64 | HTR4 (0.33) | KDM2BMAPT | |
| SCHEMBL20861635 | 0.64 | CYP11B1 (0.43) | DRD4DRD3MAPT | |
| SCHEMBL18256013 | 0.64 | CRHR1 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107623-A2 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |