Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | IL1B | P01584 | 2/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876224 | 0.87 | CRBN (0.76) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL25876220 | 0.74 | CRBN (0.74) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL19556665 | 0.73 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL19556664 | 0.73 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL476917 | 0.73 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL27097754 | 0.73 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL19503562 | 0.72 | CRBN (0.54) | CRBNDDB1CSNK1A1 | |
| SCHEMBL20128634 | 0.71 | CRBN (0.76) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL20128654 | 0.71 | CRBN (0.76) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL19503552 | 0.71 | WIZ (0.45) | CRBNDDB1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |