Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355695 | 0.80 | BACE1 (0.36) | RAB9ANPC1ALDH1A1ARKDM4E | |
| SCHEMBL18246692 | 0.80 | MAPT (0.44) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL31421962 | 0.78 | CA12 (0.39) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL31421964 | 0.78 | CA12 (0.39) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL2016743 | 0.76 | CA12 (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL31052389 | 0.76 | SORD (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL25218403 | 0.76 | SORD (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL19717306 | 0.76 | MAPT (0.69) | MAPTCA1CA2RAB9ANPC1 | |
| SCHEMBL26130363 | 0.76 | MAPT (0.41) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL19556067 | 0.75 | MAPK1 (0.47) | MAPTRAB9AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |