Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 10/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052389 | 1.00 | SORD (0.36) | SORDNUDT1DUTCA12CA1 | |
| SCHEMBL2016743 | 0.84 | CA12 (0.42) | NUDT1DUTCA12CA1CA2 | |
| SCHEMBL31403630 | 0.79 | NUDT1 (0.58) | NUDT1DUTCA12CA1CA2 | |
| SCHEMBL31052362 | 0.78 | SORD (0.38) | SORD | |
| SCHEMBL25220021 | 0.78 | SORD (0.38) | SORD | |
| SCHEMBL23355518 | 0.77 | DUT (0.34) | DUTCA12CA1CA2CA9 | |
| SCHEMBL22954884 | 0.77 | DUT (0.38) | NUDT1DUTCA12CA1CA2 | |
| SCHEMBL25619986 | 0.76 | MAPT (0.37) | NUDT1DUTCA12CA1CA2 | |
| SCHEMBL31421965 | 0.75 | CA12 (0.36) | DUTCA12CA1CA2CA9 | |
| SCHEMBL30189795 | 0.72 | DUT (0.36) | NUDT1DUTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |