Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562731 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1GAAKMT2AGLA | |
| SCHEMBL2562008 | 0.90 | CCNC (0.42) | CYP19A1CYP11B1CYP11B2BRAFEIF2AK3 | |
| SCHEMBL2562005 | 0.90 | CCNC (0.42) | CYP19A1CYP11B1CYP11B2BRAFEIF2AK3 | |
| SCHEMBL2562773 | 0.88 | HPGD (0.41) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL2560821 | 0.88 | HPGD (0.41) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL2556489 | 0.84 | CYP19A1 (0.40) | KDM4EALDH1A1GAAKMT2ACYP19A1 | |
| SCHEMBL7707992 | 0.83 | PDE4B (0.43) | KMT2ALMNAMEN1SMN1; SMN2HPGD | |
| SCHEMBL2556731 | 0.81 | CCNC (0.42) | KMT2ALMNABRAFEIF2AK3CYP1A1 | |
| SCHEMBL2557438 | 0.80 | CCNC (0.38) | CYP19A1CYP11B1CYP11B2BRAFEIF2AK3 | |
| SCHEMBL2557440 | 0.80 | CCNC (0.38) | CYP19A1CYP11B1CYP11B2BRAFEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132051-A2 | TRICYCLE COMPOUNDS AS PHOSPHODIESTERASE-10 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |