SCHEMBL25620232

SCHEMBL25620232

CCc1cccc(C/C=N/N=C/Cc2cccc(CC)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
MGLL Q99685 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
SIGMAR1 Q99720 6/20 0.37
BCL2 P10415 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
SMYD3 Q9H7B4 1/20 0.36
IDO1 P14902 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TRPA1 O75762 1/20 0.34
SLC11A2 P49281 1/20 0.34
NISCH Q9Y2I1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25620327 0.84 GRIN2D (0.39) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25620230 0.79 TAAR1 (0.49) IDO1
SCHEMBL166894 0.79 TP53 (0.61) TP53MGLLCYP1A2CYP2A6SIGMAR1
SCHEMBL7930766 0.78 MGLL (0.44) TP53MGLLCYP1A2CYP2A6BCL2
SCHEMBL25620239 0.78 IDO1 (0.43) TP53CYP2A6IDO1SMN1; SMN2TRPA1
SCHEMBL11787191 0.77 ALDH1A1 (0.46) TP53MGLLCYP1A2CYP2A6GRIN2D
SCHEMBL27992190 0.77 TP53 (0.42) TP53MGLLCYP1A2CYP2A6SIGMAR1
SCHEMBL27991970 0.77 TP53 (0.42) TP53MGLLCYP1A2CYP2A6SIGMAR1
Benzene SCHEMBL9785236 0.77 TP53 (0.67) TP53MGLLCYP1A2CYP2A6SIGMAR1
Ammonia Solution, Strong SCHEMBL28805948 0.77 TP53 (0.58) TP53MGLLCYP1A2CYP2A6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114453-A1 PHENYLETHYLIDENEHYDRAZINE DIMERS AND METHODS OF USING SAME Neurawell Therapeutics (US) 2023-06-22 WO disclosed