Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577458 | 0.80 | KIF11 (0.46) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL14099337 | 0.72 | KIF11 (0.49) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| Hydrochloric Acid SCHEMBL5125320 | 0.70 | KIF11 (0.47) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL2562101 | 0.70 | POLB (0.46) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29620952 | 0.68 | KIF11 (0.57) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL850429 | 0.68 | KIF11 (0.57) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL1964418 | 0.68 | HDAC8 (0.46) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29788387 | 0.68 | HDAC8 (0.46) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL12291843 | 0.68 | KIF11 (0.45) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL10383508 | 0.68 | AR (0.46) | KCNQ3KCNQ2KCNE1KCNQ1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132017-A1 | PYRIDO[3,4-D]PYRIMIDINYL ACETAMIDE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |