Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850429 | 1.00 | KIF11 (0.57) | KIF11LMNAMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL31439018 | 0.98 | KIF11 (0.56) | KIF11LMNAMAPK1HTTRAB9A | |
| SCHEMBL418896 | 0.86 | LMNA (0.49) | KIF11LMNAMAPK1HTTRAB9A | |
| SCHEMBL16104820 | 0.85 | LMNA (0.51) | KIF11LMNAMAPK1HTTRAB9A | |
| SCHEMBL5360083 | 0.85 | LMNA (0.47) | KIF11LMNAMAPK1HTTRAB9A | |
| SCHEMBL31438988 | 0.84 | TAS1R3 (0.54) | KIF11LMNAMAPK1HTTRAB9A | |
| SCHEMBL78878 | 0.84 | TAS1R3 (0.54) | KIF11LMNAMAPK1HTTRAB9A | |
| SCHEMBL827082 | 0.83 | RXRA (0.48) | KIF11TTRRXRARXRBRXRG | |
| SCHEMBL31319449 | 0.83 | RXRA (0.48) | KIF11TTRRXRARXRBRXRG | |
| SCHEMBL313169 | 0.82 | KIF11 (0.75) | KIF11KCNQ3KCNQ2KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003309-B | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-114846004-B | Antimalarial drugs | 德克萨斯大学系统董事会 | 2024-10-11 | — | — | CN | disclosed |
| EP-4430047-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-113024467-B | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof | 米托布里奇公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-112313209-B | Herbicidal compounds | 先正达农作物保护股份公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-113004205-B | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof | 米托布里奇公司 | 2024-07-02 | — | — | CN | disclosed |
| WO-2023081923-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Frequency Therapeutics, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-116003309-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| EP-4161916-A1 | SUBSTITUTED ISOQUINOLINYLMETHYL AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-04-12 | — | — | EP | disclosed |
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |
| EP-4077308-A1 | ANTI-MALARIAL AGENTS | The Board of Regents of the University of Texas System (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-114846004-A | Novel antimalarial drug | 德克萨斯大学系统董事会 | 2022-08-02 | — | — | CN | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |