Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559998 | 0.83 | ERN1 (0.41) | ERN1ORAI1MAPTALDH1A1CCR5 | |
| SCHEMBL15329705 | 0.76 | ERN1 (0.44) | ERN1ORAI1ALDH1A1CCR5KDM4E | |
| SCHEMBL6087632 | 0.71 | ORAI1 (0.48) | ERN1ORAI1MAPTALDH1A1CCR5 | |
| SCHEMBL30400094 | 0.71 | ORAI1 (0.48) | ERN1ORAI1MAPTALDH1A1CCR5 | |
| SCHEMBL2562612 | 0.70 | ORAI1 (0.43) | ERN1ORAI1MAPTALDH1A1CCR5 | |
| SCHEMBL2556053 | 0.70 | ALDH1A1 (0.53) | ERN1ORAI1MAPTALDH1A1CCR5 | |
| SCHEMBL2557590 | 0.69 | ERN1 (0.45) | ERN1ORAI1ALDH1A1KDM4ETDP1 | |
| SCHEMBL17513194 | 0.69 | ERN1 (0.47) | ERN1ORAI1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL32682669 | 0.69 | ERN1 (0.47) | ERN1ORAI1MAPTALDH1A1KDM4E | |
| SCHEMBL20303456 | 0.69 | ERN1 (0.47) | ERN1ORAI1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |