Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30400094 | 1.00 | ORAI1 (0.48) | ORAI1ERN1POLBALOX15HTT | |
| SCHEMBL6090664 | 0.82 | ERN1 (0.51) | ERN1POLBALOX15HTTTDP1 | |
| SCHEMBL8189636 | 0.78 | ORAI1 (0.51) | ORAI1ERN1POLBHTTTDP1 | |
| SCHEMBL17221402 | 0.78 | POLB (0.39) | ERN1POLBALOX15HTTALDH1A1 | |
| SCHEMBL2562281 | 0.77 | ALDH1A1 (0.46) | ORAI1ERN1POLBALOX15LMNA | |
| SCHEMBL5883224 | 0.75 | ORAI1 (0.56) | ORAI1ERN1POLBTDP1CYP1A2 | |
| SCHEMBL5881855 | 0.75 | ORAI1 (0.49) | ORAI1ERN1POLBTDP1CYP1A2 | |
| SCHEMBL17513175 | 0.75 | ORAI1 (0.56) | ORAI1ERN1POLBHTTTDP1 | |
| SCHEMBL3222717 | 0.75 | ORAI1 (0.49) | ORAI1ERN1POLBTDP1CYP1A2 | |
| SCHEMBL2556737 | 0.74 | TDP1 (0.49) | ORAI1ERN1HTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | claimed |
| CN-110642818-A | Method for preparing benzofuran-2-formamide compound | 云南师范大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-110642818-A | Method for preparing benzofuran-2-formamide compound | 云南师范大学 | 2020-01-03 | — | — | CN | disclosed |
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |