SCHEMBL25625979

SCHEMBL25625979

O=C1Cc2ccccc2[C@H](C(=O)N2C3OC3OC[C@@H]2Cc2ccccc2)N1CCCF

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20113023 0.80 NAAA (0.36) GRM7
SCHEMBL20113018 0.80 NAAA (0.36) GRM7
SCHEMBL19960657 0.80 NAAA (0.36) GRM7
SCHEMBL19960662 0.80 NAAA (0.36) GRM7
SCHEMBL19953523 0.75 GRM7 (0.43) GRM7
SCHEMBL19960658 0.75 GRM7 (0.43) GRM7
SCHEMBL20113077 0.75 GRM7 (0.43) GRM7
SCHEMBL19960659 0.74 NAAA (0.39) GRM7
SCHEMBL19960858 0.71 GRM7 (0.40) GRM7
SCHEMBL20166097 0.67 GRM7 (0.39) GRM7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541812-B1 MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS TAKEDA PHARMACEUTICALS CO (JP) 2023-06-14 EP disclosed