Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21369470 | 0.99 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTKDM4EPKM | |
| SCHEMBL21369617 | 0.86 | MEN1 (0.47) | ALDH1A1KDM4ETRPV4CYP2D6SMN1; SMN2 | |
| SCHEMBL20434754 | 0.85 | MEN1 (0.49) | ALDH1A1KDM4ETRPV4CYP2D6SMN1; SMN2 | |
| SCHEMBL21369466 | 0.79 | CRHR1 (0.42) | ALDH1A1HPGDKDM4ETRPV4SMN1; SMN2 | |
| SCHEMBL22964758 | 0.78 | OGA (0.43) | CYP2D6 | |
| SCHEMBL28578769 | 0.78 | OGA (0.43) | CYP2D6 | |
| SCHEMBL21369577 | 0.77 | CRHR1 (0.43) | ALDH1A1HPGDKDM4ETDP1TRPV4 | |
| SCHEMBL28569974 | 0.75 | OGA (0.37) | ALDH1A1HPGDMAPTTDP1CYP2D6 | |
| SCHEMBL21369465 | 0.75 | OGA (0.37) | ALDH1A1HPGDMAPTTDP1CYP2D6 | |
| SCHEMBL30962123 | 0.74 | OGA (0.40) | ALDH1A1TRPV4CYP2D6SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186899-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2023-05-31 | — | — | EP | disclosed |