Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503568 | 0.89 | HTT (0.44) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL3503750 | 0.88 | BRD4 (0.41) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL3502692 | 0.87 | BRD4 (0.45) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL3502504 | 0.86 | CCNA2 (0.46) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL4148044 | 0.86 | BRD4 (0.40) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL21995756 | 0.85 | BRD4 (0.43) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL25624954 | 0.85 | ALDH1A1 (0.41) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL4159155 | 0.84 | LMNA (0.42) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL12499289 | 0.83 | CCNA2 (0.46) | BRD4MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL4170831 | 0.82 | BRD4 (0.41) | BRD4MEN1KMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104178-A1 | PROTEIN KINASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 山东绿叶制药有限公司 | 2023-06-15 | — | — | WO | disclosed |