Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13013114 | 0.83 | HPGD (0.57) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL21584689 | 0.82 | HTT (0.54) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL25629645 | 0.82 | HTT (0.54) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL12518835 | 0.81 | HPGD (0.61) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL2678757 | 0.79 | CNR2 (0.49) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL26159917 | 0.79 | HTT (0.60) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL25290995 | 0.79 | NAMPT (0.44) | NAMPTCNR2EPHX2GPR183KCNH2 | |
| SCHEMBL12385902 | 0.79 | KMT2A (0.46) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL20582793 | 0.79 | CHRNB2 (0.63) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL3548644 | 0.79 | CNR2 (0.43) | NAMPTCNR2TSHRALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |