Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 5/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PPP5C | P53041 | 2/20 | 0.45 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.45 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584689 | 1.00 | HTT (0.54) | HTTLMNAHRH3NAMPTCNR2 | |
| SCHEMBL26159917 | 0.90 | HTT (0.60) | HTTLMNAHRH3NAMPTCNR2 | |
| SCHEMBL4036894 | 0.89 | HTT (0.62) | HTTLMNAHRH3CNR2PPP5C | |
| SCHEMBL26007359 | 0.85 | HTT (0.56) | HTTLMNAHRH3PPP5CPPP2CA | |
| SCHEMBL13013114 | 0.83 | HPGD (0.57) | HTTHRH3NAMPTCNR2TSHR | |
| SCHEMBL25629008 | 0.82 | NAMPT (0.43) | HTTHRH3NAMPTCNR2TSHR | |
| SCHEMBL12385902 | 0.82 | KMT2A (0.46) | NAMPTCNR2TSHRALDH1A1EPHX2 | |
| SCHEMBL12518835 | 0.81 | HPGD (0.61) | LMNAHRH3NAMPTCNR2TSHR | |
| SCHEMBL25633367 | 0.81 | HRH3 (0.56) | HRH3NAMPTCNR2 | |
| SCHEMBL26159929 | 0.81 | EPHX2 (0.47) | LMNAHRH3NAMPTCNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121413-A1 | NOVEL BICYCLIC HETEROCYCLYL COMPOUND AND USE THEREOF | 제일약품주식회사 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |
| WO-2023093832-A1 | TRICYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海济煜医药科技有限公司 | 2023-06-01 | — | — | WO | disclosed |