Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.65 |
| ▸ | NOS1 | P29475 | 6/20 | 0.65 |
| ▸ | NOS3 | P29474 | 5/20 | 0.65 |
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 4/20 | 0.48 |
| ▸ | ARG1 | P05089 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527395 | 1.00 | NOS2 (0.65) | NOS2NOS1NOS3GSRCYP2C19 | |
| SCHEMBL1527394 | 1.00 | NOS2 (0.65) | NOS2NOS1NOS3GSRCYP2C19 | |
| Hydrochloric Acid SCHEMBL8127399 | 0.98 | NOS2 (0.62) | NOS2NOS1NOS3GSRCYP2C19 | |
| SCHEMBL881063 | 0.94 | NOS2 (0.58) | NOS2NOS1NOS3GSRCYP2C19 | |
| SCHEMBL358975 | 0.94 | NOS2 (0.58) | NOS2NOS1NOS3GSRCYP2C19 | |
| SCHEMBL1527409 | 0.94 | NOS2 (0.58) | NOS2NOS1NOS3GSRCYP2C19 | |
| Hydrochloric Acid SCHEMBL15091326 | 0.92 | NOS2 (0.56) | NOS2NOS1NOS3GSRCYP2C19 | |
| Hydrochloric Acid SCHEMBL15091324 | 0.92 | NOS2 (0.56) | NOS2NOS1NOS3GSRCYP2C19 | |
| Hydrochloric Acid SCHEMBL920513 | 0.92 | NOS2 (0.56) | NOS2NOS1NOS3GSRCYP2C19 | |
| Acetic Acid SCHEMBL919118 | 0.90 | NOS2 (0.54) | NOS2NOS1NOS3GSRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4745237-A1 | RNAI AGENT FOR INHIBITING EXPRESSION OF KETOHEXOKINASE AND USE THEREOF | YUN HO BIO CO., LTD (CN) | 2026-05-20 | — | — | EP | claimed |
| WO-2025082461-A1 | POLYPEPTIDE, BIOACTIVE CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 优洛生物(上海)有限公司 | 2025-04-24 | — | — | WO | claimed |
| WO-2025016294-A1 | RNAI AGENT FOR INHIBITING EXPRESSION OF KETOHEXOKINASE AND USE THEREOF | 云合智药（苏州）生物科技有限公司 | 2025-01-23 | — | — | WO | claimed |
| CN-118804921-A | Conjugate, ligand unit and use thereof | 云合智药（苏州）生物科技有限公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2024152775-A1 | CONJUGATE, LIGAND UNIT AND USE THEREOF | 云合智药（苏州）生物科技有限公司 | 2024-07-25 | — | — | WO | claimed |
| EP-4745237-A1 | RNAI AGENT FOR INHIBITING EXPRESSION OF KETOHEXOKINASE AND USE THEREOF | YUN HO BIO CO., LTD (CN) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025082461-A1 | POLYPEPTIDE, BIOACTIVE CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 优洛生物(上海)有限公司 | 2025-04-24 | — | — | WO | disclosed |
| WO-2025016294-A1 | RNAI AGENT FOR INHIBITING EXPRESSION OF KETOHEXOKINASE AND USE THEREOF | 云合智药（苏州）生物科技有限公司 | 2025-01-23 | — | — | WO | disclosed |
| CN-118804921-A | Conjugate, ligand unit and use thereof | 云合智药（苏州）生物科技有限公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2024152775-A1 | CONJUGATE, LIGAND UNIT AND USE THEREOF | 云合智药（苏州）生物科技有限公司 | 2024-07-25 | — | — | WO | disclosed |
| WO-2023111350-A2 | CARBONIC ANHYDRASE IX LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| US-20230089867-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | NOVARTIS AG (CH) | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230089867-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | PCSK9, PCSK7, PCSK6 | NOS2 2539/4885NOS1 1051/4885NOS3 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.