SCHEMBL358975

SCHEMBL358975

CN(C)CCCC[C@H](N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 8/20 0.58
NOS1 P29475 5/20 0.58
NOS3 P29474 4/20 0.58
GSR P00390 1/20 0.57
ARG2 P78540 4/20 0.52
ARG1 P05089 3/20 0.52
CYP1A2 P05177 2/20 0.50
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.50
BLM P54132 1/20 0.49
CYP2C19 P33261 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
GLA P06280 1/20 0.46
NFKB1 P19838 1/20 0.46
APEX1 P27695 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527409 1.00 NOS2 (0.58) NOS2NOS1NOS3GSRARG2
SCHEMBL881063 1.00 NOS2 (0.58) NOS2NOS1NOS3GSRARG2
Hydrochloric Acid SCHEMBL15091324 0.98 NOS2 (0.56) NOS2NOS1NOS3GSRARG2
Hydrochloric Acid SCHEMBL920513 0.98 NOS2 (0.56) NOS2NOS1NOS3GSRARG2
Hydrochloric Acid SCHEMBL15091326 0.98 NOS2 (0.56) NOS2NOS1NOS3GSRARG2
Acetic Acid SCHEMBL919118 0.96 NOS2 (0.54) NOS2NOS1NOS3GSRARG2
SCHEMBL1527395 0.94 NOS2 (0.65) NOS2NOS1NOS3GSRARG2
SCHEMBL1527394 0.94 NOS2 (0.65) NOS2NOS1NOS3GSRARG2
SCHEMBL25629375 0.94 NOS2 (0.65) NOS2NOS1NOS3GSRARG2
Hydrochloric Acid SCHEMBL8127399 0.92 NOS2 (0.62) NOS2NOS1NOS3GSRARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745237-A1 RNAI AGENT FOR INHIBITING EXPRESSION OF KETOHEXOKINASE AND USE THEREOF YUN HO BIO CO., LTD (CN) 2026-05-20 EP claimed
WO-2026100273-A1 METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, APPARATUS FOR PRODUCING USEFUL SUBSTANCE, AND ALGAE CONTAINING USEFUL SUBSTANCE NTT株式会社 2026-05-15 WO claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
US-20250332223-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2025-10-30 US claimed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 US claimed
US-12377135-B2 GHRH antagonists for use in a method of treating sarcoidosis UNIVERSITY OF MIAMI (US) 2025-08-05 US claimed
WO-2025147774-A1 COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING AND TREATMENT OF CANCER AND OTHER DISORDERS ALPHA-9 ONCOLOGY INC. (CA) 2025-07-17 WO claimed
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US claimed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO claimed
WO-2025137441-A1 RADIOPHARMACEUTICALS TARGETING SOMATOSTATIN RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO claimed
US-20220221433-A1 MASS SPECTROMETRY ASSAY METHODS FOR DETECTION OF METABOLITES METABOLON, INC. 2022-07-14 US claimed
EP-3999095-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2022-05-25 EP claimed
US-20220143149-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2022-05-12 US claimed
WO-2022067052-A1 PROBIOTIC BACILLUS COMPOSITIONS AND METHODS OF USE ELANCO US INC. (US) 2022-03-31 WO claimed
CN-113892029-A Mass spectrometry method for detecting metabolites 梅塔博隆股份有限公司 2022-01-04 CN claimed
EP-2621919-B1 PHENYLQUINAZOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2016-01-13 EP claimed
US-7893048-B2 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions ASTRAZENECA AB (SE) 2011-02-22 US claimed
EP-1896410-A1 NOVEL 2-AZETIDINONE DERIVATIVES AS CHOLESTEROL ABSORPTION INHIBITORS FOR THE TREATMENT OF HYPERLIPIDAEMIC CONDITIONS AstraZeneca AB (SE) 2008-03-12 EP claimed
WO-2006137796-A1 NOVEL 2-AZETIDINONE DERIVATIVES AS CHOLESTEROL ABSORPTION INHIBITORS FOR THE TREATMENT OF HYPERLIPIDAEMIC CONDITIONS ASTRAZENECA AB (SE) 2006-12-28 WO claimed
US-20060013784-A1 Novel dimercaptoamides, compositions comprising them as reducing agents, and processes for permanently reshaping keratin fibers therewith L'OREAL S.A. (FR) 2006-01-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060013784-A1 Novel dimercaptoamides, compositions comprising them as reducing agents, and processes for permanently reshaping keratin fibers therewith KRT18, CKAP4, S100A4 NOS2 3625/4885NOS1 4062/4885NOS3 4202/4885
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 NOS2 3478/4885NOS1 3994/4885NOS3 3534/4885
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 NOS2 1516/4885NOS1 1882/4885NOS3 1690/4885
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof SSTR2, SSTR4, SSTR5 NOS2 3352/4885NOS1 4173/4885NOS3 4280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.