Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000704 | 0.89 | OTC (0.49) | OTCFOLH1SMN1; SMN2ALBGSR | |
| SCHEMBL25629532 | 0.89 | OTC (0.49) | OTCFOLH1SMN1; SMN2ALBGSR | |
| SCHEMBL25629484 | 0.88 | GLP1R (0.42) | OTCFOLH1ALBALDH1A1 | |
| SCHEMBL9728848 | 0.87 | OTC (0.48) | OTCFOLH1SMN1; SMN2GSRALDH1A1 | |
| SCHEMBL10000707 | 0.83 | SIGMAR1 (0.48) | OTCFOLH1SMN1; SMN2ALBALDH1A1 | |
| SCHEMBL27150498 | 0.82 | ALB (0.59) | OTCFOLH1ALBNOD1 | |
| SCHEMBL27150501 | 0.82 | ALB (0.59) | OTCFOLH1ALBNOD1 | |
| SCHEMBL20614501 | 0.81 | FOLH1 (0.43) | OTCFOLH1SMN1; SMN2ALBALDH1A1 | |
| SCHEMBL10000705 | 0.81 | SIGMAR1 (0.45) | OTCSMN1; SMN2ALDH1A1 | |
| SCHEMBL31429756 | 0.81 | FOLH1 (0.43) | OTCFOLH1SMN1; SMN2ALBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111350-A2 | CARBONIC ANHYDRASE IX LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |