Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000704 | 0.99 | OTC (0.49) | OTCFOLH1SMN1; SMN2ALDH1A1GSR | |
| SCHEMBL25629532 | 0.99 | OTC (0.49) | OTCFOLH1SMN1; SMN2ALDH1A1GSR | |
| SCHEMBL10000707 | 0.92 | SIGMAR1 (0.48) | OTCFOLH1SMN1; SMN2ALDH1A1NOD1 | |
| SCHEMBL27323887 | 0.90 | FOLH1 (0.43) | OTCFOLH1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20614501 | 0.90 | FOLH1 (0.43) | OTCFOLH1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31429756 | 0.90 | FOLH1 (0.43) | OTCFOLH1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16089032 | 0.89 | FOLH1 (0.42) | OTCFOLH1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17246791 | 0.88 | FOLH1 (0.53) | FOLH1NOD1 | |
| SCHEMBL25629482 | 0.87 | OTC (0.43) | OTCFOLH1SMN1; SMN2ALDH1A1NOD1 | |
| SCHEMBL25358822 | 0.86 | DRD2 (0.42) | OTCFOLH1NOD1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162109-A | MAGNETIC RESONANCE IMAGING AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1992-11-10 | — | — | US | disclosed |