Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPP5C | P53041 | 2/20 | 0.46 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.46 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584689 | 0.85 | HTT (0.54) | HTTLMNACYP1A2TDP1PPP5C | |
| SCHEMBL25629645 | 0.85 | HTT (0.54) | HTTLMNACYP1A2TDP1PPP5C | |
| SCHEMBL26615179 | 0.80 | HPGD (0.60) | HTTLMNATFPI2TSHRALDH1A1 | |
| SCHEMBL2075903 | 0.80 | HTT (0.81) | HTTLMNACYP1A2TDP1PPP5C | |
| SCHEMBL4036894 | 0.80 | HTT (0.62) | HTTLMNAPPP5CPPP2CATFPI2 | |
| SCHEMBL25629007 | 0.79 | HRH3 (0.51) | TSHRALDH1A1HRH3 | |
| SCHEMBL30072403 | 0.78 | HPGD (0.64) | HTTLMNATSHRALDH1A1HSD11B1 | |
| SCHEMBL16838101 | 0.78 | HTT (0.60) | HTTLMNACYP1A2TDP1PPP5C | |
| SCHEMBL8194135 | 0.78 | HTT (0.71) | HTTLMNACYP1A2TDP1PPP5C | |
| SCHEMBL25811260 | 0.78 | ALDH1A1 (0.46) | HTTTSHRALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121413-A1 | NOVEL BICYCLIC HETEROCYCLYL COMPOUND AND USE THEREOF | 제일약품주식회사 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023093832-A1 | TRICYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海济煜医药科技有限公司 | 2023-06-01 | — | — | WO | disclosed |