Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 7/20 | 0.33 |
| ▸ | HTR2C | P28335 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887912 | 0.82 | HTR2A (0.36) | HTR2AHTR2C | |
| SCHEMBL25717118 | 0.81 | HRH4 (0.33) | PDCD1CD274HTR2AHTR2C | |
| SCHEMBL22167703 | 0.79 | TLR9 (0.31) | PDCD1CD274HTR2AHTR2C | |
| SCHEMBL24097903 | 0.72 | PDCD1 (0.34) | PDCD1CD274HTR2AHTR2C | |
| SCHEMBL19495428 | 0.71 | TGFBR1 (0.48) | HTR2AHTR2C | |
| SCHEMBL929279 | 0.69 | POLB (0.47) | PDCD1CD274HTR2AHTR2C | |
| SCHEMBL10095060 | 0.69 | HTR7 (0.42) | PDCD1CD274HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL15385166 | 0.68 | POLB (0.46) | PDCD1CD274HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL1232988 | 0.68 | — | — | |
| SCHEMBL19005576 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |