SCHEMBL25629692

SCHEMBL25629692

c1ccc(-c2cccc(-n3c4ccc(-n5c6ccccc6c6ccccc65)cc4c4ccc5c6ccccc6sc5c43)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 4/20 0.35
RXFP1 Q9HBX9 1/20 0.35
TP53 P04637 3/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
ALOX5 P09917 1/20 0.33
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
HSD17B10 Q99714 1/20 0.30
FAAH O00519 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HSP90AA1 P07900 1/20 0.30
PKM P14618 1/20 0.30
HTT P42858 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653645 0.96 L3MBTL1 (0.39) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL23862203 0.96 L3MBTL1 (0.39) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL19653664 0.95 ATM (0.38) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL25629703 0.95 ATM (0.38) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL23862256 0.94 L3MBTL1 (0.40) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL19652896 0.94 L3MBTL1 (0.40) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL25629702 0.94 KDM4E (0.37) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL10014565 0.94 ATM (0.39) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL17299983 0.93 ATM (0.38) ATMKDM4EL3MBTL1MAPTRXFP1
SCHEMBL24923482 0.93 KDM4E (0.40) ATMKDM4EL3MBTL1MAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed