SCHEMBL25629702

SCHEMBL25629702

c1ccc(-c2cccc(-c3cccc(-n4c5ccc(-n6c7ccccc7c7ccccc76)cc5c5ccc6c7cc(-n8c9ccccc9c9ccccc98)ccc7sc6c54)c3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
LIMK1 P53667 1/20 0.31
TP53 P04637 1/20 0.31
RAC2 P15153 1/20 0.30
RAC3 P60763 1/20 0.30
CDC42 P60953 1/20 0.30
RAC1 P63000 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25629703 0.99 ATM (0.38) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL25629692 0.94 ATM (0.38) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL9890214 0.91 ATM (0.46) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL23862203 0.90 L3MBTL1 (0.39) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL19653645 0.90 L3MBTL1 (0.39) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL19653664 0.90 ATM (0.38) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL25630054 0.89 LIMK1 (0.33) KDM4EATML3MBTL1LIMK1
SCHEMBL19652896 0.89 L3MBTL1 (0.40) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL23862256 0.89 L3MBTL1 (0.40) KDM4EATML3MBTL1MAPTRXFP1
SCHEMBL15583069 0.89 L3MBTL1 (0.40) KDM4EATML3MBTL1MAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189544-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed