Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 3/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630891 | 0.88 | EHMT2 (0.45) | EHMT2EHMT1IGF1RAURKAAURKB | |
| SCHEMBL25630890 | 0.84 | IGF1R (0.45) | EHMT2EHMT1IGF1RAURKAAURKB | |
| SCHEMBL19476616 | 0.84 | ALK (0.44) | EHMT2EHMT1IGF1RSYKCDK2 | |
| SCHEMBL30367701 | 0.83 | EHMT2 (0.77) | EHMT2EHMT1IGF1RSYKCDK2 | |
| SCHEMBL19462482 | 0.83 | EHMT2 (0.77) | EHMT2EHMT1IGF1RSYKCDK2 | |
| SCHEMBL19476383 | 0.82 | EHMT2 (0.76) | EHMT2EHMT1IGF1RSYKCDK2 | |
| SCHEMBL23641919 | 0.81 | EHMT2 (0.61) | EHMT2EHMT1IGF1RAURKAAURKB | |
| SCHEMBL19476861 | 0.81 | EHMT2 (0.74) | EHMT2EHMT1IGF1RSYKCDK2 | |
| SCHEMBL19477462 | 0.80 | EHMT2 (0.55) | EHMT2EHMT1IGF1RAURKAAURKB | |
| SCHEMBL19476829 | 0.80 | EHMT2 (0.55) | EHMT2EHMT1IGF1RAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672800-B2 | Combination therapies with EHMT2 inhibitors | Epizyme, Inc. (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11672800-B2 | Combination therapies with EHMT2 inhibitors | EHMT2, BHMT, SHMT2 | EHMT2 1/4885EHMT1 6/4885IGF1R 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.