SCHEMBL2563180

SCHEMBL2563180

C1=Cc2nc1cc1ccc([nH]1)c(-c1ccccc1)c1nc(cc3ccc([nH]3)c2-c2ccccc2)C=C1

nearest known ligand 0.91

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.91
▸ STAT1 P42224 1/20 0.91
▸ TOP1 P11387 4/20 0.44
▸ CYCS P99999 3/20 0.43
▸ TERT O14746 4/20 0.42
▸ ENPP2 Q13822 1/20 0.39
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28908470 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
Zinc Ion SCHEMBL30574155 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
SCHEMBL30608144 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
SCHEMBL31127545 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
SCHEMBL26073065 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
SCHEMBL30574152 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
SCHEMBL29459724 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
SCHEMBL31127547 0.98 STAT3 (0.89) STAT3STAT1TOP1CYCSTERT
SCHEMBL473158 0.97 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL1224432 0.97 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119926458-A Porphyrin-based diatomic catalyst for preparing ethylene by acetylene hydrogenation and preparation method and application thereof 广西大学 2025-05-06 — — CN claimed
CN-116288357-B Chromogenic corrosive liquid and preparation method and application thereof 湖北亿纬动力有限公司 2024-10-11 — — CN claimed
WO-2024193107-A1 COLOR-DEVELOPING CORROSIVE LIQUID, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖北亿纬动力有限公司 2024-09-26 — — WO claimed
CN-115785889-B Polyurethane adhesive for single-sided adhesive shoes and preparation method thereof 福建华夏蓝新材料科技有限公司 2024-07-05 — — CN claimed
CN-115433367-B Porphyrin COF material, preparation method and application 山西大学 2023-09-22 — — CN claimed
CN-116288357-A Chromogenic corrosive liquid and preparation method and application thereof 湖北亿纬动力有限公司 2023-06-23 — — CN claimed
EP-3313519-B1 JAK-STAT INHIBITORS FOR THE TREATMENT OF CONGENITAL MYOPATHIES CHILDRENS MEDICAL CENTER (US) 2023-05-31 — — EP claimed
CN-115785889-A Polyurethane adhesive for single-sided sizing shoes and preparation method thereof 福建华夏蓝新材料科技有限公司 2023-03-14 — — CN claimed
CN-115433367-A Porphyrin COF material and preparation method and application thereof 山西大学 2022-12-06 — — CN claimed
US-20220378866-A1 COMBINATION THERAPY METHODS, COMPOSITIONS AND KITS FUNDACIÓ DE RECERCA CLÍNIC BARCELONA-INSTITUT D’INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER (ES) 2022-12-01 — — US claimed
CN-107219280-B A kind of Metalloporphyrins gas sensor element and its preparation method and application 济南大学 2019-07-05 — — CN claimed
US-20180185478-A1 TREATMENT FOR MYOPATHY CHILDREN'S MEDICAL CENTER CORPORATION (US) 2018-07-05 — — US claimed
EP-3313519-A1 TREATMENT FOR MYOPATHY Children's Medical Center Corporation (US) 2018-05-02 — — EP claimed
CN-107219280-A A kind of Metalloporphyrins gas sensor element and its preparation method and application 济南大学 2017-09-29 — — CN claimed
US-9669036-B2 Modulation of reactivation of a latent virus THE UNIVERSITY OF CHICAGO (US) 2017-06-06 — — US claimed
CN-106711400-A Anode plate and secondary battery 宁德新能源科技有限公司 2017-05-24 — — CN claimed
WO-2017004142-A1 TREATMENT FOR MYOPATHY CHILDREN'S MEDICAL CENTER CORPORATION (US) 2017-01-05 — — WO claimed
US-20030203888-A1 Chromophores WELLCOME TRUST LIMITED, THE (GB) 2003-10-30 — — US claimed
EP-1294726-A2 IMPROVEMENTS IN AND RELATING TO CHROMOPHORES Catalyst Biomedica Ltd (GB) 2003-03-26 — — EP claimed
WO-2002000662-A1 IMPROVEMENTS IN AND RELATING TO CHROMOPHORES CATALYST BIOMEDICA LIMITED (GB) 2002-01-03 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220378866-A1 COMBINATION THERAPY METHODS, COMPOSITIONS AND KITS S1PR3, S1PR1, S1PR2 STAT3 10/4885STAT1 38/4885TOP1 4173/4885
US-20030203888-A1 Chromophores HCCS, PPOX, HMBS STAT3 3257/4885STAT1 4092/4885TOP1 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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