Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.61 |
| ▸ | MMP2 | P08253 | 9/20 | 0.45 |
| ▸ | MMP9 | P14780 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.45 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | FCER2 | P06734 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24141313 | 0.81 | CACNA2D1 (0.38) | MMECACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL23346343 | 0.81 | CACNA2D1 (0.38) | MMECACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL19825789 | 0.79 | MME (0.38) | MMEMMP2MMP9MMP1MMP3 | |
| SCHEMBL26672708 | 0.79 | MME (0.38) | MMEMMP2MMP9MMP1MMP3 | |
| SCHEMBL7368385 | 0.79 | MME (0.81) | MMEMMP2MMP9MMP1MMP3 | |
| SCHEMBL25633002 | 0.79 | MME (0.63) | MMEMMP2MMP9MMP1CACNA2D1 | |
| SCHEMBL23805327 | 0.78 | CACNA2D1 (0.36) | MMECACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL21564122 | 0.78 | CACNA2D1 (0.36) | MMECACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL21994104 | 0.77 | MME (0.67) | MMEMMP2MMP9MMP1MMP3 | |
| SCHEMBL25633017 | 0.76 | MME (0.51) | MMEMMP2MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SSB, UACA, CDA | MME 4628/4885MMP2 4243/4885MMP9 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.