Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494977 | 0.79 | NAALAD2 (0.45) | NAALAD2FOLH1ENPEPMMEACE | |
| SCHEMBL21195111 | 0.78 | SLC1A1 (0.52) | ALDH1A1 | |
| SCHEMBL422585 | 0.78 | — | — | |
| SCHEMBL22278772 | 0.77 | NAALAD2 (0.52) | NAALAD2FOLH1ALDH1A1KDM4EMAPT | |
| SCHEMBL4801958 | 0.75 | CTSK (0.46) | NAALAD2FOLH1CA1CA2 | |
| SCHEMBL14049211 | 0.75 | PLA2G10 (0.56) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3587007 | 0.74 | NAALAD2 (0.41) | NAALAD2FOLH1ALDH1A1MAPTBLM | |
| SCHEMBL16283422 | 0.74 | MME (0.64) | MMEACEMMEL1 | |
| SCHEMBL1144276 | 0.72 | CRAT (0.41) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL7731906 | 0.72 | CRAT (0.41) | ALDH1A1KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SSB, UACA, CDA | NAALAD2 772/4885FOLH1 160/4885ALDH1A1 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.