Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.65 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 5/20 | 0.39 |
| ▸ | MMP9 | P14780 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.39 |
| ▸ | MMP7 | P09237 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | FCER2 | P06734 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25633002 | 0.86 | MME (0.63) | MMEMMP2MMP9MMP8MMP7 | |
| SCHEMBL20628537 | 0.78 | MME (0.69) | MMEMMP2MMP9MMP8MMP7 | |
| SCHEMBL25633190 | 0.77 | MME (0.55) | MMEBIRC2MMP2MMP9MMP8 | |
| SCHEMBL13857484 | 0.74 | CYP2C9 (0.43) | MMP2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL8269110 | 0.72 | MME (0.61) | MMEBIRC2MMP2MMP9MMP8 | |
| SCHEMBL15928856 | 0.72 | MME (0.51) | MMEALDH1A1ACEMEN1LMNA | |
| SCHEMBL13857486 | 0.71 | ALDH1A1 (0.41) | MMEMMP2ALDH1A1ACELMNA | |
| SCHEMBL13857488 | 0.71 | CTSC (0.34) | MMP2ALDH1A1LMNAMMP1MMP3 | |
| SCHEMBL19696456 | 0.70 | MME (0.50) | MMEBIRC2MMP2MMP9MMP8 | |
| SCHEMBL17770755 | 0.70 | MME (0.50) | MMEBIRC2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SSB, UACA, CDA | MME 4628/4885BIRC2 2526/4885MMP2 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.