Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30073546 | 0.94 | NLRP3 (0.59) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL25633360 | 0.91 | NLRP3 (0.55) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL25220683 | 0.86 | NLRP3 (0.54) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL25634319 | 0.86 | NLRP3 (0.71) | NLRP3THRBTP53MAPTNPC1 | |
| SCHEMBL30073579 | 0.86 | NLRP3 (0.54) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL30073597 | 0.85 | NLRP3 (0.53) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL25633881 | 0.85 | NLRP3 (0.53) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL25634001 | 0.85 | NLRP3 (0.53) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL30528660 | 0.84 | NLRP3 (0.62) | NLRP3THRBTP53MAPTRXFP1 | |
| SCHEMBL25633362 | 0.84 | NLRP3 (0.51) | NLRP3THRBTP53MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183249-A1 | NEW TRIAZINOINDOLE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183249-A1 | NEW TRIAZINOINDOLE COMPOUNDS | NLRP3, NLRP1, PYCARD | NLRP3 1/4885THRB 277/4885TP53 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.