Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.30 |
| ▸ | NOS3 | P29474 | 2/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18762570 | 0.83 | ODC1 (0.31) | NOS2NOS3NOS1 | |
| Nv-5138 SCHEMBL18762500 | 0.83 | SLC7A5 (0.41) | NOS2NOS3NOS1 | |
| SCHEMBL18774931 | 0.83 | ODC1 (0.31) | NOS2NOS3NOS1 | |
| Nv-5138 SCHEMBL18774929 | 0.83 | SLC7A5 (0.41) | NOS2NOS3NOS1 | |
| SCHEMBL18762569 | 0.83 | ODC1 (0.31) | NOS2NOS3NOS1 | |
| Nv-5138 SCHEMBL18762589 | 0.83 | SLC7A5 (0.41) | NOS2NOS3NOS1 | |
| SCHEMBL24831970 | 0.78 | — | — | |
| SCHEMBL17792713 | 0.77 | NOS2 (0.33) | NOS2NOS3NOS1 | |
| SCHEMBL12782323 | 0.77 | DPP4 (0.41) | — | |
| SCHEMBL15086350 | 0.77 | DPP4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | GATD3, GABRR2, GABRR3 | NOS2 1608/4885NOS3 2146/4885NOS1 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.