Uridine

Uridine

SCHEMBL2563446

O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=c1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.78

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.78
SLC28A2 O43868 1/20 0.78
SLC29A1 Q99808 1/20 0.78
SLC28A3 Q9HAS3 1/20 0.78
P2RY2 P41231 9/20 0.56
P2RY6 Q15077 6/20 0.56
DUT P33316 2/20 0.55
P2RY4 P51582 3/20 0.55
P2RY14 Q15391 4/20 0.53
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TK1 P04183 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL20268100 0.92 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL20268097 0.92 SLC28A1 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Deoxyuridine SCHEMBL9708874 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT
Deoxyuridine SCHEMBL2641582 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT
Deoxyuridine SCHEMBL114598 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT
Deoxyuridine SCHEMBL24512520 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT
Deoxyuridine SCHEMBL19841232 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT
Deoxyuridine SCHEMBL4847464 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT
Deoxyuridine SCHEMBL391224 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT
Deoxyuridine SCHEMBL9219265 0.91 DUT (0.64) SLC28A1SLC28A2SLC29A1SLC28A3DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011123811-A2 PRODUCTION OF POST-TRANSLATIONALLY HYDROXYLATED RECOMBINANT PROTEINS IN BACTERIA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-10-06 WO disclosed