Deoxyuridine

Deoxyuridine

SCHEMBL2641582

O=c1ccn(C2CC(O)C(CO)O2)c(=O)[nH]1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DUT P33316 3/20 0.64
TK1 P04183 3/20 0.62
LMNA P02545 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
ALOX12 P18054 1/20 0.58
ADRA1A P35348 1/20 0.58
TK2 O00142 1/20 0.57
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyuridine SCHEMBL9219261 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL889540 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL114598 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL19841232 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL9708874 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL24512520 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL4847464 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL391224 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL9219265 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1
Deoxyuridine SCHEMBL28844 1.00 DUT (0.64) DUTTK1LMNASMN1; SMN2SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US disclosed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 US disclosed
EP-4543898-A1 PYRIMIDINE NUCLEOSIDE TREATMENTS The Children's Medical Center Corporation (US) 2025-04-30 EP disclosed
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides ARVINAS OPERATIONS, INC. (US) 2024-07-16 US disclosed
US-11912699-B2 Tau-protein targeting compounds and associated ARVINAS OPERATIONS, INC. (US) 2024-02-27 US disclosed
WO-2024020221-A1 MODULATORS OF TYK2 PROTEOLYSIS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. (US) 2024-01-25 WO disclosed
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
WO-2023250015-A1 PYRIMIDINE NUCLEOSIDE TREATMENTS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-12-28 WO disclosed
US-11707452-B2 Modulators of alpha-synuclein proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2023-07-25 US disclosed
US-7517646-B2 Functional molecule and process for producing the same FUJITSU LIMITED (JP) 2009-04-14 US disclosed
US-20080214404-A1 Functional molecule binding specifically to membrane protein, and manufacturing method therefor FUJITSU LIMITED (JP) 2008-09-04 US disclosed
US-20080214404-A1 Functional molecule binding specifically to membrane protein, and manufacturing method therefor FUJITSU LIMITED (JP) 2008-09-04 US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 US disclosed
US-20070232793-A1 Functional molecule and manufacturing method therefor FUJITSU LIMITED (JP) 2007-10-04 US disclosed
US-20070232793-A1 Functional molecule and manufacturing method therefor FUJITSU LIMITED (JP) 2007-10-04 US disclosed
US-20070231855-A1 Functional molecule and manufacturing method therefor FUJITSU LIMITED (JP) 2007-10-04 US disclosed
US-20070231855-A1 Functional molecule and manufacturing method therefor FUJITSU LIMITED (JP) 2007-10-04 US disclosed
US-20070190546-A1 Methods and compositions for sequencing a nucleic acid FLUIDIGM CORPORATION 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912699-B2 Tau-protein targeting compounds and associated MAPT, VHL, CRBN DUT 3691/4885TK1 1825/4885LMNA 2024/4885
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides IRAK1, IRAK4, IRAK2 DUT 3897/4885TK1 372/4885LMNA 2696/4885
US-20070232793-A1 Functional molecule and manufacturing method therefor TNFSF11, VSIG8, ADAM8 DUT 2142/4885TK1 3668/4885LMNA 3016/4885
US-11707452-B2 Modulators of alpha-synuclein proteolysis and associated methods of use UCHL1, ADRM1, CRBN DUT 3328/4885TK1 2497/4885LMNA 1946/4885
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION COL2A1, COLGALT1, PLOD3 DUT 1409/4885TK1 2622/4885LMNA 287/4885
US-20070190546-A1 Methods and compositions for sequencing a nucleic acid RNGTT, POLN, NT5C3B DUT 54/4885TK1 189/4885LMNA 537/4885
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use LRRK2, ADRM1, CRBN DUT 4113/4885TK1 2291/4885LMNA 2534/4885
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei RCC1, NUMA1, ACIN1 DUT 269/4885TK1 17/4885LMNA 107/4885
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME SQSTM1, BECN1, CUTA DUT 4183/4885TK1 2352/4885LMNA 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.