Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248048 | 0.83 | CTSL (0.36) | GRNSORT1KDM4EMAPTTHRB | |
| SCHEMBL20166237 | 0.83 | CTSL (0.36) | GRNSORT1KDM4EMAPTTHRB | |
| SCHEMBL20166234 | 0.83 | CTSL (0.36) | GRNSORT1KDM4EMAPTTHRB | |
| Hydrochloric Acid SCHEMBL20166215 | 0.82 | CTSL (0.35) | GRNSORT1KDM4EMAPTTHRB | |
| Hydrochloric Acid SCHEMBL20166214 | 0.82 | CTSL (0.35) | GRNSORT1KDM4EMAPTTHRB | |
| Hydrochloric Acid SCHEMBL345244 | 0.82 | GRN (0.33) | GRNSORT1KDM4EMAPTTHRB | |
| Bromide SCHEMBL347137 | 0.82 | GRN (0.33) | GRNSORT1KDM4EMAPTTHRB | |
| SCHEMBL16056904 | 0.81 | KDM4E (0.34) | GRNSORT1KDM4EMAPTTHRB | |
| Hydrochloric Acid SCHEMBL20166212 | 0.80 | CTSL (0.35) | GRNSORT1KDM4EMAPTTHRB | |
| Bromide SCHEMBL16057768 | 0.79 | KDM4E (0.33) | GRNSORT1KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | GATD3, GABRR2, GABRR3 | GRN 2185/4885SORT1 2332/4885KDM4E 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.