Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26962906 | 0.95 | ADRA1A (0.46) | ADRA1ANAMPT | |
| SCHEMBL26962913 | 0.83 | NAMPT (0.41) | ADRA1ANAMPT | |
| SCHEMBL3771644 | 0.82 | NAMPT (0.53) | NAMPT | |
| SCHEMBL2925583 | 0.82 | ADRA1A (0.53) | ADRA1A | |
| SCHEMBL2590973 | 0.80 | HPGD (0.51) | NAMPT | |
| SCHEMBL3766585 | 0.78 | CHRNB2 (0.51) | NAMPT | |
| SCHEMBL27228118 | 0.77 | NAMPT (0.53) | NAMPT | |
| SCHEMBL28612826 | 0.77 | ADRA1A (0.54) | ADRA1A | |
| Hydrochloric Acid SCHEMBL2569336 | 0.77 | CHRNB2 (0.50) | NAMPT | |
| SCHEMBL2573737 | 0.76 | ADRA1A (0.52) | ADRA1ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066659-B1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2013-08-28 | — | — | EP | disclosed |
| EP-2383267-A1 | Substituted sulfonamide derivatives | Grünenthal GmbH (DE) | 2011-11-02 | — | — | EP | disclosed |
| EP-2066659-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008040492-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-04-10 | — | — | WO | disclosed |