SCHEMBL25636247

SCHEMBL25636247

CC(C)c1ccc(N(c2ccccc2)c2cc(-c3ccccc3)c3ccc4c(N(c5ccccc5)c5ccccc5)cc(-c5ccccc5)c5ccc2c3c54)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.38
CRHR1 P34998 3/20 0.35
KIF11 P52732 1/20 0.35
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
KDM1A O60341 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
MAPT P10636 3/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12576978 1.00 METAP2 (0.38) METAP2CRHR1KIF11CNR1CNR2
SCHEMBL19051122 0.95 METAP2 (0.35) METAP2CRHR1KIF11CNR1CNR2
SCHEMBL24488550 0.95 METAP2 (0.35) METAP2CRHR1KIF11CNR1CNR2
SCHEMBL24041239 0.95 METAP2 (0.35) METAP2CRHR1KIF11CNR1CNR2
SCHEMBL23921030 0.95 METAP2 (0.35) METAP2CRHR1KIF11CNR1CNR2
SCHEMBL19080428 0.93 CRHR1 (0.36) METAP2CRHR1KIF11KDM1AALDH1A1
SCHEMBL12577224 0.92 CNR2 (0.33) METAP2CRHR1KIF11CNR1CNR2
SCHEMBL24050251 0.92 METAP2 (0.36) METAP2CRHR1KIF11PTGS1LMNA
SCHEMBL12577068 0.89 AKR1C3 (0.39) METAP2CRHR1KIF11KDM1AALDH1A1
SCHEMBL25492381 0.89 CRHR1 (0.32) METAP2CRHR1GAAMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165022-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230165022-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed