Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551523 | 0.83 | POLB (0.47) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL18746420 | 0.81 | ATM (0.44) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL10591282 | 0.75 | POLB (0.52) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL12138845 | 0.74 | KDM4E (0.45) | MEN1KMT2AALDH1A1HSD17B10GAA | |
| SCHEMBL24161132 | 0.74 | KMT2A (0.49) | IP6K1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL15320780 | 0.74 | ALDH1A1 (0.48) | POLBALDH1A1HSD17B10USP2TSHR | |
| SCHEMBL52686 | 0.74 | LMNA (0.57) | POLBALDH1A1HSD17B10USP2TSHR | |
| SCHEMBL4324119 | 0.73 | NR4A2 (0.49) | MEN1KMT2AALDH1A1TSHRNR4A1 | |
| SCHEMBL4890014 | 0.73 | KDM4E (0.47) | MEN1KMT2AALDH1A1NR4A1NR4A2 | |
| SCHEMBL15320367 | 0.72 | ALDH1A1 (0.44) | POLBALDH1A1HSD17B10USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552915-A1 | COMPOUNDS AND METHOD FOR TREATMENT OF HIV | Critical Outcome Technologies, Inc. (CA) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120153-A1 | COMPOUNDS AND METHOD FOR TREATMENT OF HIV | CRITICAL OUTCOME TECHNOLOGIES INC. (CA) | 2011-10-06 | — | — | WO | disclosed |