Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12120573 | 0.77 | EGFR (0.42) | EGFR | |
| SCHEMBL13054413 | 0.76 | GABRA1 (0.36) | EGFRP2RX3P2RX2 | |
| SCHEMBL23178631 | 0.73 | — | — | |
| SCHEMBL24915897 | 0.73 | CYP1A2 (0.36) | — | |
| SCHEMBL12338360 | 0.73 | MAPT (0.43) | P2RX3P2RX2 | |
| SCHEMBL10200874 | 0.72 | EGFR (0.35) | EGFR | |
| SCHEMBL16746141 | 0.72 | EGFR (0.34) | EGFR | |
| SCHEMBL19297211 | 0.71 | P2RX3 (0.30) | P2RX3P2RX2 | |
| SCHEMBL19297140 | 0.71 | P2RX3 (0.30) | P2RX3P2RX2 | |
| SCHEMBL2737342 | 0.70 | P2RX3 (0.33) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181546-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | PLIANT THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181546-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | ITGA5, ITGAL, ITGB5 | EGFR 769/4885P2RX3 3407/4885P2RX2 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.