Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30118870 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1TYMSCTSB | |
| SCHEMBL6048769 | 0.82 | MEN1 (0.48) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL30488438 | 0.82 | MEN1 (0.48) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL28063139 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1TYMSCTSB | |
| SCHEMBL18338685 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1TYMSCTSB | |
| SCHEMBL6786414 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TDP1TYMSMEN1 | |
| SCHEMBL18424404 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TDP1TYMSCTSB | |
| SCHEMBL3469093 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TDP1TYMSCTSB | |
| SCHEMBL27540387 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL597745 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116122057-A | High-strength cold-resistant textile for aerospace use and manufacturing method thereof | 西京学院 | 2023-05-16 | — | — | CN | claimed |
| US-20230219986-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-07-13 | — | — | US | disclosed |
| US-20230219986-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-07-13 | — | — | US | disclosed |
| US-20230192734-A1 | TRICYCLIC COMPOUNDS AS EGFR INHIBITORS | QILU PHARMACEUTICAL CO LTD (CN) | 2023-06-22 | — | — | US | disclosed |
| CN-116122057-A | High-strength cold-resistant textile for aerospace use and manufacturing method thereof | 西京学院 | 2023-05-16 | — | — | CN | disclosed |
| CN-115667226-A | Tricyclic compounds as EGFR inhibitors | 齐鲁制药有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2022059778-A1 | CYCLIC UREA DERIVATIVE | カルナバイオサイエンス株式会社 | 2022-03-24 | — | — | WO | disclosed |
| CN-107635558-A | Bu Luomo domain inhibitor | 赛尔基因昆蒂赛尔研究公司 | 2018-01-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192734-A1 | TRICYCLIC COMPOUNDS AS EGFR INHIBITORS | EGFR, ERBB2, ERBB3 | ALDH1A1 3656/4885CYP3A4 3056/4885TDP1 2926/4885 |
| US-20230219986-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | EGFR, ERBB2, ERBB4 | ALDH1A1 2690/4885CYP3A4 3314/4885TDP1 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.