SCHEMBL2563789

SCHEMBL2563789

C=C[C@@H](N)c1ccc(C=O)nc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 1/20 0.35
CCR1 P32246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2553936 1.00 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL25912492 0.79 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL2552973 0.78 ADRB2 (0.38) KCNJ1CCR1
SCHEMBL15330558 0.78 ADRB2 (0.38) KCNJ1CCR1
SCHEMBL15331456 0.75 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL2553741 0.75 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL15329724 0.75 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL15331646 0.75 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL15330307 0.74 KCNJ1 (0.34) KCNJ1CCR1
SCHEMBL15331602 0.74 KCNJ1 (0.34) KCNJ1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed