SCHEMBL25638189

SCHEMBL25638189

COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(=O)O)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 13/20 0.45
▸ XIAP P98170 2/20 0.45
▸ REN P00797 1/20 0.41
▸ CMA1 P23946 4/20 0.41
▸ MLX Q9UH92 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30134415 1.00 ELANE (0.45) ELANEXIAPRENCMA1MLX
SCHEMBL25637921 0.93 ELANE (0.46) ELANEXIAPRENCMA1MLX
SCHEMBL21581232 0.90 ELANE (0.42) ELANEXIAPRENCMA1MLX
SCHEMBL10297466 0.90 ELANE (0.42) ELANEXIAPRENCMA1MLX
SCHEMBL10297438 0.90 ELANE (0.42) ELANEXIAPRENCMA1MLX
SCHEMBL29463845 0.90 ELANE (0.42) ELANEXIAPRENCMA1MLX
SCHEMBL8615903 0.87 XIAP (0.48) ELANEXIAPCMA1MLX
SCHEMBL8920639 0.87 XIAP (0.48) ELANEXIAPCMA1MLX
SCHEMBL17029371 0.86 ELANE (0.40) ELANEXIAPRENCMA1MLX
SCHEMBL10297455 0.86 ELANE (0.40) ELANEXIAPRENCMA1MLX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102044-A1 SUBSTRATE-BASED PROBES FOR MONITORING PROTEASE ACTIVITY USING MALDI-TOFMS ZETEO TECH, INC. (US) 2026-05-15 — — WO disclosed
EP-4739399-A2 METHODS AND COMPOSITIONS FOR ULTRAVIOLET PROTECTION OF SKIN Mary Kay, Inc. (US) 2026-05-13 — — EP disclosed
EP-4734912-A2 HIGH SEPARATION DUAL PHASE EYE MAKE-UP REMOVER Mary Kay, Inc. (US) 2026-05-06 — — EP disclosed
WO-2025264660-A1 COSMETIC COMPOSITION COMPRISING CAFFEINE AND MELATONIN MARY KAY INC. (US) 2025-12-26 — — WO disclosed
US-20250360075-A1 TOPICAL COMPOSITIONS AND METHODS MARY KAY INC. (US) 2025-11-27 — — US disclosed
EP-4642419-A1 COSMETIC COMPOSITIONS AND METHODS OF USING SAME Mary Kay, Inc. (US) 2025-11-05 — — EP disclosed
WO-2025137712-A1 COSMETIC COMPOSITIONS AND METHODS OF USING SAME MARY KAY INC. (US) 2025-06-26 — — WO disclosed
US-20250099625-A1 TANDEM MOLECULAR FLUORESCENCE REPORTERS FOR DETECTION OF TUMOR-INFILTRATING LEUKOCYTES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-27 — — US disclosed
WO-2025014750-A2 METHODS AND COMPOSITIONS FOR ULTRAVIOLET PROTECTION OF SKIN MARY KAY INC. (US) 2025-01-16 — — WO disclosed
WO-2025006980-A2 HIGH SEPARATION DUAL PHASE EYE MAKE-UP REMOVER MARY KAY INC. (US) 2025-01-02 — — WO disclosed
EP-4146158-A1 COSMETIC COMPOSITION COMPRISING GLUCONOLACTONE AND GLYCOLIC ACID Mary Kay, Inc. (US) 2023-03-15 — — EP disclosed
EP-4142684-A1 COSMETIC COMPOSITIONS AND METHODS COMPRISING PLUMERIA ALBA FLOWER EXTRACT Mary Kay, Inc. (US) 2023-03-08 — — EP disclosed
EP-4138775-A1 TOPICAL COSMETIC COMPOSITIONS Mary Kay, Inc. (US) 2023-03-01 — — EP disclosed
EP-4138773-A1 TOPICAL COSMETIC COMPOSITIONS Mary Kay, Inc. (US) 2023-03-01 — — EP disclosed
WO-2023279086-A1 TOPICAL COMPOSITION AGAINST FINE LINES AND WRINKLES MARY KAY INC. (US) 2023-01-05 — — WO disclosed
EP-3324925-B1 TOPICAL SKIN FORMULATIONS MARY KAY INC (US) 2022-12-14 — — EP disclosed
EP-4096619-A1 LIP COMPOSITION Mary Kay, Inc. (US) 2022-12-07 — — EP disclosed
EP-4072513-A1 HERBAL COSMETIC COMPOSITION FOR TREATING SKIN Mary Kay, Inc. (US) 2022-10-19 — — EP disclosed
WO-2022192882-A1 TOPICAL COMPOSITIONS FOR UV PROTECTION MARY KAY INC. (US) 2022-09-15 — — WO disclosed
US-20220249359-A1 COSMETIC COMPOSITIONS AND METHODS FOR THEIR USE IN FIRMING SKIN MARY KAY INC. 2022-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099625-A1 TANDEM MOLECULAR FLUORESCENCE REPORTERS FOR DETECTION OF TUMOR-INFILTRATING LEUKOCYTES GZMB, GUSB, MKI67 ELANE 181/4885XIAP 1492/4885REN 587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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