SCHEMBL29463845

SCHEMBL29463845

COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)CCl)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 11/20 0.42
▸ XIAP P98170 2/20 0.39
▸ REN P00797 1/20 0.39
▸ CMA1 P23946 3/20 0.37
▸ MLX Q9UH92 1/20 0.37
▸ BIRC2 Q13490 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21581232 1.00 ELANE (0.42) ELANEXIAPRENCMA1MLX
SCHEMBL10297438 1.00 ELANE (0.42) ELANEXIAPRENCMA1MLX
SCHEMBL10297466 1.00 ELANE (0.42) ELANEXIAPRENCMA1MLX
SCHEMBL10297455 0.96 ELANE (0.40) ELANEXIAPRENCMA1MLX
SCHEMBL10297429 0.96 ELANE (0.40) ELANEXIAPRENCMA1MLX
SCHEMBL17029371 0.96 ELANE (0.40) ELANEXIAPRENCMA1MLX
SCHEMBL29463850 0.92 REN (0.40) ELANEXIAPRENCMA1MLX
SCHEMBL25637921 0.91 ELANE (0.46) ELANEXIAPRENCMA1MLX
SCHEMBL30134415 0.90 ELANE (0.45) ELANEXIAPRENCMA1MLX
SCHEMBL25638189 0.90 ELANE (0.45) ELANEXIAPRENCMA1MLX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12134796-B2 Methods of prediction of wound healing WOUNDCHEK LABORATORIES (US), INC. (US) 2024-11-05 — — US claimed
EP-3353316-B1 METHODS OF PREDICTION OF WOUND HEALING WOUNDCHEK LABORATORIES INC (US) 2024-01-10 — — EP claimed
US-20230127290-A1 MUSCLE REGENERATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-04-27 — — US claimed
EP-4746881-A1 NEW CRYSTALLINE FORMS OF A DIPEPTIDYL-PEPTIDASE I INHIBITOR AND ITS USE IN THERAPY Boehringer Ingelheim International GmbH (DE) 2026-05-27 — — EP disclosed
EP-4735111-A1 SINGLE-DOMAIN ANTIBODY FOR INHIBITION OF NEUTROPHIL ELASTASE ACTIVITY Université de Liège (BE) 2026-05-06 — — EP disclosed
US-20260060930-A1 New crystalline Forms, new pharmaceutical Composition and Dose Regimen of a Dipeptidyl peptidase I inhibitor for the Treatment of Patients with Bronchiectasis or other DPP-I mediated Diseases BOEHRINGER INGELHEIM INT (DE) 2026-03-05 — — US disclosed
WO-2026046911-A1 A DIPEPTIDYL-PEPTIDASE I INHIBITOR FOR ITS USE IN THE TREATMENT OF ANCA-ASSOCIATED VASCULITIS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-03-05 — — WO disclosed
US-20250282740-A1 COMPOSITIONS FOR TREATING AND/OR PREVENTING CELL OR TISSUE NECROSIS SPECIFICALLY TARGETING CATHEPSIN C AND/OR CELA1 AND/OR CELA3A AND/OR STRUCTURALLY RELATED ENZYMES THERETO Ela Pharma Ltd (IL) 2025-09-11 — — US disclosed
EP-4597115-A2 PEPTIDE QUANTITATION ASSAY FOR DIFFERENTIATING FULL-LENGTH HIGH MOLECULAR WEIGHT KININOGEN (HMWK) AND CLEAVED HMWK Takeda Pharmaceutical Company Limited (JP) 2025-08-06 — — EP disclosed
EP-4574040-A2 EVACUATED BLOOD COLLECTION TUBES CONTAINING PROTEASE INHIBITORS FOR THE ASSESSMENT OF CONTACT SYSTEM ACTIVATION Takeda Pharmaceutical Company Limited (JP) 2025-06-25 — — EP disclosed
US-20250172567-A1 PEPTIDE QUANTITATION ASSAY FOR DIFFERENTIATING FULL-LENGTH HIGH MOLECULAR WEIGHT KININOGEN (HMWK) AND CLEAVED HMWK TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-05-29 — — US disclosed
US-20230182139-A1 EVACUATED BLOOD COLLECTION TUBES CONTAINING PROTEASE INHIBITORS FOR THE ASSESSMENT OF CONTACT SYSTEM ACTIVATION TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-06-15 — — US disclosed
US-11668718-B2 Peptide quantitation assay for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-06-06 — — US disclosed
EP-3334343-B1 EVACUATED BLOOD COLLECTION TUBES CONTAINING PROTEASE INHIBITORS FOR THE ASSESSMENT OF CONTACT SYSTEM ACTIVATION TAKEDA PHARMACEUTICALS CO (JP) 2022-10-19 — — EP disclosed
US-11458477-B2 Evacuated blood collection tubes containing protease inhibitors for the assessment of contact system activation TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-10-04 — — US disclosed
CN-110547288-B Blood processing method and blood collection tube 爱科来株式会社 2022-09-02 — — CN disclosed
CN-114981661-A Method for diagnosing fibrinolytic insufficiency associated with neutrophil extracellular traps 斯特拉斯堡大学医院 2022-08-30 — — CN disclosed
CN-114716390-A Compositions and methods for treating and/or preventing necrosis of cells or tissue ELA制药有限公司 2022-07-08 — — CN disclosed
EP-4005569-A2 COMPOSITIONS FOR TREATING AND/OR PREVENTING CELL OR TISSUE NECROSIS SPECIFICALLY TARGETING CATHEPSIN C AND/OR CELA1 AND/OR CELA3A AND/OR STRUCTURALLY RELATED ENZYMES THERETO ELA Pharma Ltd (IL) 2022-06-01 — — EP disclosed
CN-107690429-B Composition for the treatment and/or prevention of necrosis of cells or tissue, specifically targeting cathepsin C and/or CELA1 and/or CELA3A and/or enzymes structurally related thereto ELA制药有限公司 2022-02-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060930-A1 New crystalline Forms, new pharmaceutical Composition and Dose Regimen of a Dipeptidyl peptidase I inhibitor for the Treatment of Patients with Bronchiectasis or other DPP-I mediated Diseases CTSC, DPP3, SERPINB1 ELANE 35/4885XIAP 394/4885REN 155/4885
US-20250282740-A1 COMPOSITIONS FOR TREATING AND/OR PREVENTING CELL OR TISSUE NECROSIS SPECIFICALLY TARGETING CATHEPSIN C AND/OR CELA1 AND/OR CELA3A AND/OR STRUCTURALLY RELATED ENZYMES THERETO CELA1, CTSG, CTSE ELANE 36/4885XIAP 144/4885REN 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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