SCHEMBL25638567

SCHEMBL25638567

CC(C)C(=O)NC(C(=O)N1CCCC1C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
ELANE P08246 2/20 0.38
DPP4 P27487 6/20 0.37
FAP Q12884 4/20 0.37
DPP8 Q6V1X1 3/20 0.37
DPP9 Q86TI2 3/20 0.37
PREP P48147 3/20 0.37
DPP7 Q9UHL4 2/20 0.37
BIRC2 Q13490 5/20 0.35
XIAP P98170 1/20 0.35
BIRC3 Q13489 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10080104 0.89 DPP4 (0.41) ELANEDPP4FAPDPP8DPP9
SCHEMBL10078889 0.88 BIRC2 (0.45) ELANEDPP4FAPPREPBIRC2
SCHEMBL18754863 0.88 BIRC2 (0.45) ELANEDPP4FAPPREPBIRC2
SCHEMBL13073348 0.87 DPP4 (0.39) ELANEDPP4FAPDPP8DPP9
SCHEMBL20707055 0.85 DPP4 (0.45) ELANEDPP4FAPDPP8DPP9
SCHEMBL15765626 0.85 DPP4 (0.45) ELANEDPP4FAPDPP8DPP9
SCHEMBL23959219 0.84 DPP4 (0.40) ELANEDPP4FAPDPP8DPP9
SCHEMBL15304291 0.83 ELANE (0.43) ELANEBIRC2XIAPBIRC3
SCHEMBL12402520 0.83 NR1I2 (0.40)
SCHEMBL12293760 0.83 NR1I2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023097251-A1 OLIGONUCLEOTIDE-CONTAINING TRANSCRIPTION FACTOR TARGETING CHIMERAS YALE UNIVERSITY (US) 2023-06-01 WO disclosed