Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032817 | 1.00 | CASP3 (0.53) | CASP3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2563393 | 1.00 | CASP3 (0.53) | CASP3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL910267 | 1.00 | CASP3 (0.53) | CASP3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28682050 | 0.86 | NPC1 (0.50) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL24654500 | 0.86 | KLK7 (0.53) | CASP3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL415617 | 0.86 | CASP3 (0.51) | CASP3ALDH1A1MEN1KMT2AMAPT | |
| Propham SCHEMBL8536412 | 0.85 | SMN1; SMN2 (0.66) | CASP3ALDH1A1MEN1KMT2AMAPT | |
| Propham SCHEMBL67344 | 0.85 | SMN1; SMN2 (0.66) | CASP3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6379411 | 0.84 | MAPT (0.58) | ALDH1A1MAPTKLK7HPGDALOX15 | |
| SCHEMBL22500626 | 0.84 | HSD17B10 (0.54) | ALDH1A1MEN1KMT2AMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132083-A2 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2011-10-27 | — | — | WO | disclosed |