SCHEMBL415617

SCHEMBL415617

CC(OC(=O)Nc1ccccc1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.51
KLK7 P49862 1/20 0.49
GRM5 P41594 3/20 0.47
HPGD P15428 2/20 0.46
ALOX15 P16050 1/20 0.46
ALDH1A1 P00352 4/20 0.46
GAA P10253 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 1/20 0.46
NPC1 O15118 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
RAB9A P51151 1/20 0.46
POLB P06746 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2564007 0.86 CASP3 (0.53) CASP3KLK7GRM5HPGDALOX15
SCHEMBL910267 0.86 CASP3 (0.53) CASP3KLK7GRM5HPGDALOX15
SCHEMBL1032817 0.86 CASP3 (0.53) CASP3KLK7GRM5HPGDALOX15
SCHEMBL2563393 0.86 CASP3 (0.53) CASP3KLK7GRM5HPGDALOX15
Propham SCHEMBL2231188 0.84 SMN1; SMN2 (0.60) KLK7GRM5HPGDALOX15ALDH1A1
SCHEMBL24654500 0.83 KLK7 (0.53) CASP3KLK7HPGDALOX15ALDH1A1
Propham SCHEMBL67344 0.82 SMN1; SMN2 (0.66) CASP3KLK7HPGDALOX15ALDH1A1
Propham SCHEMBL8536412 0.82 SMN1; SMN2 (0.66) CASP3KLK7HPGDALOX15ALDH1A1
SCHEMBL11358778 0.80 SMN1; SMN2 (0.50) CASP3KLK7GRM5HPGDALOX15
Propham SCHEMBL28077800 0.80 SMN1; SMN2 (0.64) CASP3KLK7HPGDALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277230-A1 PARTHENOGENESIS METHODS AND COMPOSITIONS PIONEER HI-BRED INTERNATONAL, INC. (US) 2025-09-04 US disclosed
US-20240002877-A1 PARTHENOGENESIS FACTORS AND METHODS OF USING SAME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-04 US disclosed
US-9121032-B2 Selective ablation of diploid embryos E I DU PONT DE NEMOURS AND COMPANY (US) 2015-09-01 US disclosed
US-8859846-B2 Doubling of chromosomes in haploid embryos E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-14 US disclosed
US-20120311736-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E.I. du Pont de Nemours and Company and Pioneer Hi-Bred International 2012-12-06 US disclosed
US-8269061-B2 Selective ablation of diploid embryos E.I. du Pont de Nmeours and Company (US) 2012-09-18 US disclosed
US-20120023612-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL, INC. (US) 2012-01-26 US disclosed
US-20080216191-A1 Pollinating silks of maize ear, contacting haploid embryo with chromosome doubling agent (colchicine), propagate cells; generating homozygosity in plants PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-09-04 US disclosed
EP-0083613-B1 N-PHENYLPYRAZOLE DERIVATIVES USEFUL AS HERBICIDES MAY & BAKER LIMITED (GB) 1988-06-01 EP disclosed
EP-0084033-B1 N-PHENYLPYRAZOLE DERIVATIVES MAY & BAKER LIMITED (GB) 1985-10-02 EP disclosed
EP-0053011-B1 NEW HERBICIDAL NICOTINAMIDE DERIVATIVES MAY & BAKER LIMITED (GB) 1985-04-03 EP disclosed