Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23386506 | 0.92 | S1PR4 (0.37) | S1PR4KDM1A | |
| SCHEMBL23386500 | 0.82 | S1PR4 (0.36) | S1PR4KDM1A | |
| SCHEMBL25643125 | 0.79 | SLC6A15 (0.38) | S1PR4KDM1A | |
| SCHEMBL23480816 | 0.78 | KDM1A (0.38) | KDM1A | |
| SCHEMBL23480694 | 0.74 | BCL2L11 (0.37) | S1PR4 | |
| SCHEMBL26194443 | 0.73 | KDM1A (0.45) | KDM1A | |
| SCHEMBL23386596 | 0.71 | SLC6A15 (0.39) | S1PR4KDM1A | |
| SCHEMBL17565610 | 0.71 | KDM1A (0.43) | KDM1A | |
| SCHEMBL26314795 | 0.70 | KDM1A (0.38) | KDM1A | |
| SCHEMBL17565611 | 0.69 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667652-B2 | MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667652-B2 | MCL1 inhibitors | MCL1, BCL2L1, BCLAF1 | S1PR4 2446/4885KDM1A 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.