Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.33 |
| ▸ | BCL2L11 | O43521 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23442105 | 0.90 | KDM1A (0.39) | KDM1AKDM4CSIGMAR1SMN1; SMN2CYP2C19 | |
| SCHEMBL17565610 | 0.83 | KDM1A (0.43) | KDM1AKDM4CSIGMAR1CYP2C19SRD5A1 | |
| SCHEMBL26194443 | 0.83 | KDM1A (0.45) | KDM1AKDM4CSIGMAR1CYP2C19SRD5A1 | |
| SCHEMBL25643125 | 0.77 | SLC6A15 (0.38) | KDM1AKDM4CSMN1; SMN2PPARGPPARD | |
| SCHEMBL26194442 | 0.77 | LMNA (0.39) | SMN1; SMN2MEN1LMNAMAPTKMT2A | |
| SCHEMBL23442101 | 0.77 | KDM1A (0.41) | KDM1AKDM4CSIGMAR1SMN1; SMN2SRD5A1 | |
| SCHEMBL23442097 | 0.77 | KDM1A (0.41) | KDM1AKDM4CSIGMAR1SMN1; SMN2SRD5A1 | |
| SCHEMBL26314917 | 0.75 | HCAR3 (0.39) | SMN1; SMN2MEN1LMNAMAPTKMT2A | |
| SCHEMBL17542361 | 0.75 | KDM1A (0.44) | KDM1AKDM4CSIGMAR1SRD5A1MCL1 | |
| SCHEMBL17542298 | 0.75 | KDM1A (0.44) | KDM1AKDM4CSIGMAR1SRD5A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760736-B2 | Processes and intermediates for preparing MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760736-B2 | Processes and intermediates for preparing MCL1 inhibitors | MCL1, BAK1, BCL3 | KDM1A 563/4885KDM4C 2667/4885SIGMAR1 4148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.